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Syntaxin clusters at secretory granules in a munc18-bound conformation

Syntaxin (stx)-1 is an integral plasma membrane protein that is crucial for two distinct steps of regulated exocytosis, docking of secretory granules at the plasma membrane and membrane fusion. During docking, stx1 clusters at the granule docking site, together with the S/M protein munc18. Here we d...

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Detalles Bibliográficos
Autores principales: Yin, Peng, Gandasi, Nikhil R., Arora, Swati, Omar-Hmeadi, Muhmmad, Saras, Jan, Barg, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249827/
https://www.ncbi.nlm.nih.gov/pubmed/30156474
http://dx.doi.org/10.1091/mbc.E17-09-0541