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On the relation between filament density, force generation, and protrusion rate in mesenchymal cell motility

Lamellipodia are flat membrane protrusions formed during mesenchymal motion. Polymerization at the leading edge assembles the actin filament network and generates protrusion force. How this force is supported by the network and how the assembly rate is shared between protrusion and network retrograd...

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Detalles Bibliográficos
Autores principales: Dolati, Setareh, Kage, Frieda, Mueller, Jan, Müsken, Mathias, Kirchner, Marieluise, Dittmar, Gunnar, Sixt, Michael, Rottner, Klemens, Falcke, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249830/
https://www.ncbi.nlm.nih.gov/pubmed/30156465
http://dx.doi.org/10.1091/mbc.E18-02-0082