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Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development

Mice that lack the epidermal growth factor receptor (EGFR) fail to develop a hair coat, but the mechanism responsible for this deficit is not completely understood. Here, we show that EGFR plays a critical role to attenuate wingless-type MMTV integration site family member (Wnt)/β-catenin signaling...

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Detalles Bibliográficos
Autores principales: Tripurani, Swamy K., Wang, Yan, Fan, Ying-Xin, Rahimi, Massod, Wong, Lily, Lee, Min-Hyung, Starost, Matthew F., Rubin, Jeffrey S., Johnson, Gibbes R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249831/
https://www.ncbi.nlm.nih.gov/pubmed/30188763
http://dx.doi.org/10.1091/mbc.E18-08-0488