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Activation of the apoptotic pathway during prolonged prometaphase blocks daughter cell proliferation
When untransformed human cells spend >1.5 h in prometaphase under standard culture conditions, all daughters arrest in G1 despite normal division of their mothers. We investigate what happens during prolonged prometaphase that leads to daughter cell arrest in the absence of DNA damage. We find th...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249836/ https://www.ncbi.nlm.nih.gov/pubmed/30133342 http://dx.doi.org/10.1091/mbc.E18-01-0026 |