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Geometric partitioning of cohesin and condensin is a consequence of chromatin loops

SMC (structural maintenance of chromosomes) complexes condensin and cohesin are crucial for proper chromosome organization. Condensin has been reported to be a mechanochemical motor capable of forming chromatin loops, while cohesin passively diffuses along chromatin to tether sister chromatids. In b...

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Detalles Bibliográficos
Autores principales: Lawrimore, Josh, Doshi, Ayush, Friedman, Brandon, Yeh, Elaine, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249845/
https://www.ncbi.nlm.nih.gov/pubmed/30207827
http://dx.doi.org/10.1091/mbc.E18-02-0131