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A constitutive active allele of the transcription factor Msn2 mimicking low PKA activity dictates metabolic remodeling in yeast

In yeast, protein kinase A (PKA) adjusts transcriptional profiles, metabolic rates, and cell growth in accord with carbon source availability. PKA affects gene expression mostly via the transcription factors Msn2 and Msn4, two key regulators of the environmental stress response. Here we analyze the...

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Detalles Bibliográficos
Autores principales: Pfanzagl, Vera, Görner, Wolfram, Radolf, Martin, Parich, Alexandra, Schuhmacher, Rainer, Strauss, Joseph, Reiter, Wolfgang, Schüller, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249869/
https://www.ncbi.nlm.nih.gov/pubmed/30256697
http://dx.doi.org/10.1091/mbc.E18-06-0389