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Abl2 is recruited to ventral actin waves through cytoskeletal interactions to promote lamellipodium extension

Abl family nonreceptor tyrosine kinases regulate changes in cell shape and migration. Abl2 localizes to dynamic actin-rich protrusions, such as lamellipodia in fibroblasts and dendritic spines in neurons. Abl2 interactions with cortactin, an actin filament stabilizer, are crucial for the formation a...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Lyu, Wanqing, Yu, Ji, Koleske, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249870/
https://www.ncbi.nlm.nih.gov/pubmed/30256707
http://dx.doi.org/10.1091/mbc.E18-01-0044