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Abl2 is recruited to ventral actin waves through cytoskeletal interactions to promote lamellipodium extension
Abl family nonreceptor tyrosine kinases regulate changes in cell shape and migration. Abl2 localizes to dynamic actin-rich protrusions, such as lamellipodia in fibroblasts and dendritic spines in neurons. Abl2 interactions with cortactin, an actin filament stabilizer, are crucial for the formation a...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249870/ https://www.ncbi.nlm.nih.gov/pubmed/30256707 http://dx.doi.org/10.1091/mbc.E18-01-0044 |