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Stem cell library screen identified ruxolitinib as regulator of osteoblastic differentiation of human skeletal stem cells
BACKGROUND: Better understanding of the signaling pathways that regulate human bone marrow stromal stem cell (hBMSC) differentiation into bone-forming osteoblasts is crucial for their clinical use in regenerative medicine. Chemical biology approaches using small molecules targeting specific signalin...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249887/ https://www.ncbi.nlm.nih.gov/pubmed/30463599 http://dx.doi.org/10.1186/s13287-018-1068-x |