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Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model

BACKGROUND: The great diversity of molecules found in spider venoms include amino acids, polyamines, proteins and peptides, among others. Some of these compounds can interact with different neuronal receptors and ion channels including those present in the ocular system. To study potential toxicity...

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Detalles Bibliográficos
Autores principales: Silva, Flavia Rodrigues da, Paiva, Mayara Rodrigues Brandão de, Dourado, Lays Fernanda Nunes, Silva, Rummenigge Oliveira, Silva, Carolina Nunes da, Costa, Bruna Lopes da, Toledo, Cibele Rodrigues, de Lima, Maria Elena, Silva-Cunha, Armando da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249906/
https://www.ncbi.nlm.nih.gov/pubmed/30479614
http://dx.doi.org/10.1186/s40409-018-0168-5