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Intravitreal injection of the synthetic peptide LyeTx I b, derived from a spider toxin, into the rabbit eye is safe and prevents neovascularization in a chorio-allantoic membrane model
BACKGROUND: The great diversity of molecules found in spider venoms include amino acids, polyamines, proteins and peptides, among others. Some of these compounds can interact with different neuronal receptors and ion channels including those present in the ocular system. To study potential toxicity...
Autores principales: | Silva, Flavia Rodrigues da, Paiva, Mayara Rodrigues Brandão de, Dourado, Lays Fernanda Nunes, Silva, Rummenigge Oliveira, Silva, Carolina Nunes da, Costa, Bruna Lopes da, Toledo, Cibele Rodrigues, de Lima, Maria Elena, Silva-Cunha, Armando da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249906/ https://www.ncbi.nlm.nih.gov/pubmed/30479614 http://dx.doi.org/10.1186/s40409-018-0168-5 |
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