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Drug repositioning using drug-disease vectors based on an integrated network

BACKGROUND: Diverse interactions occur between biomolecules, such as activation, inhibition, expression, or repression. However, previous network-based studies of drug repositioning have employed interaction on the binary protein-protein interaction (PPI) network without considering the characterist...

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Detalles Bibliográficos
Autores principales: Lee, Taekeon, Yoon, Youngmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249928/
https://www.ncbi.nlm.nih.gov/pubmed/30463505
http://dx.doi.org/10.1186/s12859-018-2490-x