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Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2(Akita) mouse

BACKGROUND: Early-stage diabetic retinopathy (DR) is characterized by neurovascular defects. In this study, we hypothesized that human adipose-derived stem cells (ASCs) positive for the pericyte marker CD140b, or their secreted paracrine factors, therapeutically rescue early-stage DR features in an...

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Detalles Bibliográficos
Autores principales: Elshaer, Sally L., Evans, William, Pentecost, Mickey, Lenin, Raji, Periasamy, Ramesh, Jha, Kumar Abhiram, Alli, Shanta, Gentry, Jordy, Thomas, Samuel M., Sohl, Nicolas, Gangaraju, Rajashekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249931/
https://www.ncbi.nlm.nih.gov/pubmed/30463601
http://dx.doi.org/10.1186/s13287-018-1059-y