RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection In Vivo

Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines. It requires interaction with an adaptor molecule, mitochondrial antiviral-signaling protein (MAVS), to activate downstream signaling pathways. To elucidate th...

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Detalles Bibliográficos
Autores principales: Wu, Wenxin, Wang, Xiaoqiu, Zhang, Wei, Tian, Lili, Booth, J. Leland, Duggan, Elizabeth S., More, Sunil, Liu, Lin, Dozmorov, Mikhail, Metcalf, Jordan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250004/
https://www.ncbi.nlm.nih.gov/pubmed/30532653
http://dx.doi.org/10.1155/2018/6808934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250004/
https://www.ncbi.nlm.nih.gov/pubmed/30532653
http://dx.doi.org/10.1155/2018/6808934

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