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RIG-I Signaling via MAVS Is Dispensable for Survival in Lethal Influenza Infection In Vivo

Retinoic acid-inducible gene I (RIG-I) is an important regulator of virus-induced antiviral interferons (IFNs) and proinflammatory cytokines. It requires interaction with an adaptor molecule, mitochondrial antiviral-signaling protein (MAVS), to activate downstream signaling pathways. To elucidate th...

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Detalles Bibliográficos
Autores principales:	Wu, Wenxin, Wang, Xiaoqiu, Zhang, Wei, Tian, Lili, Booth, J. Leland, Duggan, Elizabeth S., More, Sunil, Liu, Lin, Dozmorov, Mikhail, Metcalf, Jordan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250004/ https://www.ncbi.nlm.nih.gov/pubmed/30532653 http://dx.doi.org/10.1155/2018/6808934

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