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Effects of Low- and High-Mineral Content Water on the Relative Bioavailability of a Coformulated Abacavir/Dolutegravir/Lamivudine Dispersible Tablet in Healthy Adults

BACKGROUND: The fixed-dose combination (FDC) tablet formulation of abacavir/dolutegravir/lamivudine is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighing ≥40 kg. Alternative formulations with acceptable palatability and convenient dosing are needed for children...

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Detalles Bibliográficos
Autores principales: Singh, Rajendra P., Shaik, Jafar S. B., Skoura, Nancy, Joshi, Shashidhar, Shreeves, Trevor, Casillas, Linda, Buchanan, Ann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250255/
https://www.ncbi.nlm.nih.gov/pubmed/30239425
http://dx.doi.org/10.1097/QAI.0000000000001859