P7C3-A20 neuroprotection is independent of Wallerian degeneration in primary neuronal culture

The antiapoptotic, neuroprotective compound P7C3-A20 reduces neurological deficits when administered to murine in-vivo models of traumatic brain injury. P7C3-A20 is thought to exert its activity through small-molecule activation of the enzyme nicotinamide phosphoribosyltransferase. This enzyme conve...

Descripción completa

Detalles Bibliográficos
Autores principales: Hill, Ciaran S., Menon, David K., Coleman, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Cellular, Molecular and Developmental Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250284/
https://www.ncbi.nlm.nih.gov/pubmed/30334859
http://dx.doi.org/10.1097/WNR.0000000000001146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250284/
https://www.ncbi.nlm.nih.gov/pubmed/30334859
http://dx.doi.org/10.1097/WNR.0000000000001146

Ejemplares similares