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P7C3-A20 neuroprotection is independent of Wallerian degeneration in primary neuronal culture

The antiapoptotic, neuroprotective compound P7C3-A20 reduces neurological deficits when administered to murine in-vivo models of traumatic brain injury. P7C3-A20 is thought to exert its activity through small-molecule activation of the enzyme nicotinamide phosphoribosyltransferase. This enzyme conve...

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Detalles Bibliográficos
Autores principales:	Hill, Ciaran S., Menon, David K., Coleman, Michael P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Cellular, Molecular and Developmental Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250284/ https://www.ncbi.nlm.nih.gov/pubmed/30334859 http://dx.doi.org/10.1097/WNR.0000000000001146

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