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Response of germline BRCA2-mutated advanced pancreatic acinar cell carcinoma to olaparib: A case report

RATIONALE: Pancreatic acinar cell carcinoma (PACC) is a relatively rare malignancy of the exocrine pancreas. BRCA2, a cancer susceptibility gene, has been widely studied in breast and ovarian carcinomas as mutation carriers for this gene are at a high risk for cancer development. Olaparib, an oral p...

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Detalles Bibliográficos
Autores principales: Li, Mao, Mou, Yu, Hou, Shengzhong, Cao, Dan, Li, Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250555/
https://www.ncbi.nlm.nih.gov/pubmed/30407325
http://dx.doi.org/10.1097/MD.0000000000013113