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Primary tumor-derived exosomes facilitate metastasis by regulating adhesion of circulating tumor cells via SMAD3 in liver cancer

Hepatocellular carcinoma (HCC) is a fatal disease and patients with HCC frequently die from metastasis. The mechanisms of HCC metastasis are not completely understood. In the present study, in vitro and in vivo data showed that HCC cells promoted cancer cell proliferation and lung metastases formati...

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Detalles Bibliográficos
Autores principales: Fu, Qihan, Zhang, Qi, Lou, Yu, Yang, Jiaqi, Nie, Gang, Chen, Qi, Chen, Yiwen, Zhang, Jingying, Wang, Jianxin, Wei, Tao, Qin, Hao, Dang, Xiaowei, Bai, Xueli, Liang, Tingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250679/
https://www.ncbi.nlm.nih.gov/pubmed/29991801
http://dx.doi.org/10.1038/s41388-018-0391-0