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The intellectual disability gene PQBP1 rescues Alzheimer’s disease pathology

Early-phase pathologies of Alzheimer’s disease (AD) are attracting much attention after clinical trials of drugs designed to remove beta-amyloid (Aβ) aggregates failed to recover memory and cognitive function in symptomatic AD patients. Here, we show that phosphorylation of serine/arginine repetitiv...

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Detalles Bibliográficos
Autores principales: Tanaka, Hikari, Kondo, Kanoh, Chen, Xigui, Homma, Hidenori, Tagawa, Kazuhiko, Kerever, Aurelian, Aoki, Shigeki, Saito, Takashi, Saido, Takaomi, Muramatsu, Shin-ichi, Fujita, Kyota, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250680/
https://www.ncbi.nlm.nih.gov/pubmed/30283027
http://dx.doi.org/10.1038/s41380-018-0253-8