BET Inhibition Improves NASH and Liver Fibrosis

Non-alcoholic fatty liver disease (NAFLD) is a leading form of chronic liver disease with large unmet need. Non-alcoholic steatohepatitis (NASH), a progressive variant of NAFLD, can lead to fibrosis, cirrhosis, and hepatocellular carcinoma. To identify potential new therapeutics for NASH, we used a...

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Detalles Bibliográficos
Autores principales: Middleton, Sarah A., Rajpal, Neetu, Cutler, Leanne, Mander, Palwinder, Rioja, Inmaculada, Prinjha, Rab K., Rajpal, Deepak, Agarwal, Pankaj, Kumar, Vinod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250695/
https://www.ncbi.nlm.nih.gov/pubmed/30467325
http://dx.doi.org/10.1038/s41598-018-35653-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250695/
https://www.ncbi.nlm.nih.gov/pubmed/30467325
http://dx.doi.org/10.1038/s41598-018-35653-4

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