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BET Inhibition Improves NASH and Liver Fibrosis
Non-alcoholic fatty liver disease (NAFLD) is a leading form of chronic liver disease with large unmet need. Non-alcoholic steatohepatitis (NASH), a progressive variant of NAFLD, can lead to fibrosis, cirrhosis, and hepatocellular carcinoma. To identify potential new therapeutics for NASH, we used a...
Autores principales: | Middleton, Sarah A., Rajpal, Neetu, Cutler, Leanne, Mander, Palwinder, Rioja, Inmaculada, Prinjha, Rab K., Rajpal, Deepak, Agarwal, Pankaj, Kumar, Vinod |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250695/ https://www.ncbi.nlm.nih.gov/pubmed/30467325 http://dx.doi.org/10.1038/s41598-018-35653-4 |
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