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A link between plasma membrane calcium ATPase 2 (PMCA2), estrogen and estrogen receptor α signaling in mechanical pain

Earlier studies on genetically modified mice indicated that plasma membrane calcium ATPase 2 (PMCA2), a calcium extrusion pump, plays a novel and sex-dependent role in mechanical pain responses: female, but not male, PMCA2(+/−) mice manifest increased mechanical pain compared to female PMCA2(+/+) mi...

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Detalles Bibliográficos
Autores principales: Khariv, Veronika, Acioglu, Cigdem, Ni, Li, Ratnayake, Ayomi, Li, Lun, Tao, Yuan-Xiang, Heary, Robert F., Elkabes, Stella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250714/
https://www.ncbi.nlm.nih.gov/pubmed/30467368
http://dx.doi.org/10.1038/s41598-018-35263-0