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Grail attenuates influenza A virus infection and pathogenesis by inhibiting viral nucleoprotein

Grail is a well-characterized mediator of metabolic disease, tumour progression, and immune response. However, its role in influenza A virus (IAV) infection remains poorly understood. In this study, we demonstrated that Grail knockdown potentiates IAV infection, whereas Grail overexpression blocks I...

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Detalles Bibliográficos
Autores principales: Lin, Hui-Tsu, Chen, Cheng-Cheung, Liu, Pei-Yao, Wu, Hsueh-Ling, Wu, Ti-Hui, Huang, Chih-Heng, Chen, Ying-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250720/
https://www.ncbi.nlm.nih.gov/pubmed/30467324
http://dx.doi.org/10.1038/s41598-018-35722-8