Cargando…

Neuroprotection by Heat Shock Factor-1 (HSF1) and Trimerization-Deficient Mutant Identifies Novel Alterations in Gene Expression

Heat shock factor-1 (HSF1) protects neurons from death caused by the accumulation of misfolded proteins by stimulating the transcription of genes encoding heat shock proteins (HSPs). This stimulatory action depends on the association of trimeric HSF1 to sequences within HSP gene promoters. However,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qu, Zhe, Titus, Anto Sam Crosslee Louis Sam, Xuan, Zhenyu, D’Mello, Santosh R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250741/ https://www.ncbi.nlm.nih.gov/pubmed/30467350 http://dx.doi.org/10.1038/s41598-018-35610-1

Ejemplares similares

The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repression
por: Louis Sam Titus, Anto Sam Crosslee, et al.
Publicado: (2019)

Heat Shock Proteins and HSF1 in Cancer
por: Cyran, Anna M., et al.
Publicado: (2022)

HSF1 and HSF3 cooperatively regulate the heat shock response in lizards
por: Takii, Ryosuke, et al.
Publicado: (2017)

Feedback regulation of heat shock factor 1 (Hsf1) activity by Hsp70‐mediated trimer unzipping and dissociation from DNA
por: Kmiecik, Szymon W, et al.
Publicado: (2020)

HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes
por: Kovács, Dániel, et al.
Publicado: (2019)

The Emerging Role of Heat Shock Factor 1 (HSF1) and Heat Shock Proteins (HSPs) in Ferroptosis
por: Aolymat, Iman, et al.
Publicado: (2023)

Genetic Selection for Constitutively Trimerized Human HSF1 Mutants Identifies a Role for Coiled-Coil Motifs in DNA Binding
por: Neef, Daniel W., et al.
Publicado: (2013)

Novel Isoforms of Heat Shock Transcription Factor 1, HSF1γα and HSF1γβ, Regulate Chaperone Protein Gene Transcription
por: Neueder, Andreas, et al.
Publicado: (2014)

Catalytic-independent neuroprotection by SIRT1 is mediated through interaction with HDAC1
por: Pfister, Jason A., et al.
Publicado: (2019)

Heat shock transcription factor 1 is SUMOylated in the activated trimeric state
por: Kmiecik, Szymon W., et al.
Publicado: (2021)

Heat shock factor 1 (HSF1) specifically potentiates c-MYC-mediated transcription independently of the canonical heat shock response
por: Xu, Meng, et al.
Publicado: (2023)

Riluzole Increases the Amount of Latent HSF1 for an Amplified Heat Shock Response and Cytoprotection
por: Yang, Jingxian, et al.
Publicado: (2008)

Molecular mechanism of thermosensory function of human heat shock transcription factor Hsf1
por: Hentze, Nikolai, et al.
Publicado: (2016)

Dynamic control of Hsf1 during heat shock by a chaperone switch and phosphorylation
por: Zheng, Xu, et al.
Publicado: (2016)

The heat shock factor HSF1 juggles protein quality control and metabolic regulation
por: Cantó, Carles
Publicado: (2017)

The SIRT1 Modulators AROS and DBC1 Regulate HSF1 Activity and the Heat Shock Response
por: Raynes, Rachel, et al.
Publicado: (2013)

Structures of heat shock factor trimers bound to DNA
por: Feng, Na, et al.
Publicado: (2021)

Baseline Elevations of Leukotriene Metabolites and Altered Plasmalogens Are Prognostic Biomarkers of Plaque Progression in Systemic Lupus Erythematosus
por: Baig, Sahar, et al.
Publicado: (2022)

Stress tolerance in diapausing embryos of Artemia franciscana is dependent on heat shock factor 1 (Hsf1)
por: Tan, Jiabo, et al.
Publicado: (2018)

PARP1 Might Substitute HSF1 to Reactivate Latent HIV-1 by Binding to Heat Shock Element
por: Xu, Xinfeng, et al.
Publicado: (2022)

Neuroprotective Effects of HSF1 in Retinal Ischemia-Reperfusion Injury
por: Liu, Wei, et al.
Publicado: (2019)

HDAC6–ubiquitin interaction controls the duration of HSF1 activation after heat shock
por: Pernet, Lydia, et al.
Publicado: (2014)

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock
por: Liebelt, Frauke, et al.
Publicado: (2019)

Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells
por: Amirkavei, Mooud, et al.
Publicado: (2022)

Resistin, Elastase, and Lactoferrin as Potential Plasma Biomarkers of Pediatric Inflammatory Bowel Disease Based on Comprehensive Proteomic Screens
por: Louis Sam Titus, Anto Sam Crosslee, et al.
Publicado: (2022)

Increased expression of heat shock factor 1 (HSF1) is associated with poor survival in gastric cancer patients
por: Dai, Weigang, et al.
Publicado: (2018)

mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis
por: Chou, Shiuh-Dih, et al.
Publicado: (2012)

Lack of Hikeshi activates HSF1 activity under normal conditions and disturbs the heat-shock response
por: Kose, Shingo, et al.
Publicado: (2022)

A Novel Mouse HSF3 Has the Potential to Activate Nonclassical Heat-Shock Genes during Heat Shock
por: Fujimoto, Mitsuaki, et al.
Publicado: (2010)

Gambogic acid and gambogenic acid induce a thiol-dependent heat shock response and disrupt the interaction between HSP90 and HSF1 or HSF2
por: Pesonen, Linda, et al.
Publicado: (2021)

Association of HSF1 Genetic Variation with Heat Tolerance in Chinese Cattle
por: Rong, Yu, et al.
Publicado: (2019)

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens
por: Vanarsa, Kamala, et al.
Publicado: (2021)

Excitatory synapse impairment and mitochondrial dysfunction in Huntington’s disease: heat shock factor 1 (HSF1) converging mechanisms
por: Zarate, Nicole, et al.
Publicado: (2019)

Opposing Effects of Sirtuins on Neuronal Survival: SIRT1-Mediated Neuroprotection Is Independent of Its Deacetylase Activity
por: Pfister, Jason A., et al.
Publicado: (2008)

Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor (Hsf1) can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor
por: Millson, Stefan H., et al.
Publicado: (2014)

Activation of the heat shock transcription factor Hsf1 is essential for the full virulence of the fungal pathogen Candida albicans
por: Nicholls, Susan, et al.
Publicado: (2011)

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response
por: Meijering, Roelien A. M., et al.
Publicado: (2015)

Transcellular chaperone signaling is an intercellular stress-response distinct from the HSF-1–mediated heat shock response
por: Miles, Jay, et al.
Publicado: (2023)

Transcriptional responses of cancer cells to heat shock-inducing stimuli involve amplification of robust HSF1 binding
por: Dastidar, Sayantani Ghosh, et al.
Publicado: (2023)

HSF1 physically neutralizes amyloid oligomers to empower overgrowth and bestow neuroprotection
por: Tang, Zijian, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_m29o7l68qr76fcpl3ksni41la6