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Reduced Efficacy of d-Amphetamine and 3,4-Methylenedioxymethamphetamine in Inducing Hyperactivity in Mice Lacking the Postsynaptic Scaffolding Protein SHANK1

Genetic defects in the three SH3 and multiple ankyrin repeat domains (SHANK) genes (SHANK1, SHANK2, and SHANK3) are associated with multiple major neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia (SCZ), and bipolar disorder (BPD). Psychostimulant-induced hyperactiv...

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Detalles Bibliográficos
Autores principales: Sungur, A. Özge, Redecker, Tobias M., Andres, Elena, Dürichen, Wiebke, Schwarting, Rainer K. W., del Rey, Adriana, Wöhr, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250831/
https://www.ncbi.nlm.nih.gov/pubmed/30505269
http://dx.doi.org/10.3389/fnmol.2018.00419