Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer

AIM: To uncover the roles of tumor-promoting gene ZEB1 in aerobic glycolysis regulation and shed light on the underlying molecular mechanism. METHODS: Endogenous zinc finger E-box binding homeobox-1 (ZEB1) was silenced using a lentivirus-mediated method, and the impact of ZEB1 and methyl-CpG binding...

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Detalles Bibliográficos
Autores principales: Xu, Wen-Yan, Hu, Qiang-Sheng, Qin, Yi, Zhang, Bo, Liu, Wen-Sheng, Ni, Quan-Xing, Xu, Jin, Yu, Xian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250915/
https://www.ncbi.nlm.nih.gov/pubmed/30487699
http://dx.doi.org/10.3748/wjg.v24.i43.4893

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250915/
https://www.ncbi.nlm.nih.gov/pubmed/30487699
http://dx.doi.org/10.3748/wjg.v24.i43.4893

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