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Zinc finger E-box-binding homeobox 1 mediates aerobic glycolysis via suppression of sirtuin 3 in pancreatic cancer
AIM: To uncover the roles of tumor-promoting gene ZEB1 in aerobic glycolysis regulation and shed light on the underlying molecular mechanism. METHODS: Endogenous zinc finger E-box binding homeobox-1 (ZEB1) was silenced using a lentivirus-mediated method, and the impact of ZEB1 and methyl-CpG binding...
Autores principales: | Xu, Wen-Yan, Hu, Qiang-Sheng, Qin, Yi, Zhang, Bo, Liu, Wen-Sheng, Ni, Quan-Xing, Xu, Jin, Yu, Xian-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250915/ https://www.ncbi.nlm.nih.gov/pubmed/30487699 http://dx.doi.org/10.3748/wjg.v24.i43.4893 |
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