Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data

BACKGROUND: Tumour budding is an important prognostic factor in colorectal cancer (CRC). Molecular profiling of tumour buds suggests (partial) epithelial–mesenchymal transition and cancer stem-cell phenotype, similarly described in the “mesenchymal” Consensus Molecular Subtype 4 (CMS4), which identi...

Descripción completa

Detalles Bibliográficos
Autores principales: Trinh, Anne, Lädrach, Claudia, Dawson, Heather E., ten Hoorn, Sanne, Kuppen, Peter J. K., Reimers, Marlies S., Koopman, Miriam, Punt, Cornelis J. A., Lugli, Alessandro, Vermeulen, Louis, Zlobec, Inti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251036/
https://www.ncbi.nlm.nih.gov/pubmed/30385823
http://dx.doi.org/10.1038/s41416-018-0230-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251036/
https://www.ncbi.nlm.nih.gov/pubmed/30385823
http://dx.doi.org/10.1038/s41416-018-0230-7

Ejemplares similares