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Tumour budding is associated with the mesenchymal colon cancer subtype and RAS/RAF mutations: a study of 1320 colorectal cancers with Consensus Molecular Subgroup (CMS) data

BACKGROUND: Tumour budding is an important prognostic factor in colorectal cancer (CRC). Molecular profiling of tumour buds suggests (partial) epithelial–mesenchymal transition and cancer stem-cell phenotype, similarly described in the “mesenchymal” Consensus Molecular Subtype 4 (CMS4), which identi...

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Detalles Bibliográficos
Autores principales:	Trinh, Anne, Lädrach, Claudia, Dawson, Heather E., ten Hoorn, Sanne, Kuppen, Peter J. K., Reimers, Marlies S., Koopman, Miriam, Punt, Cornelis J. A., Lugli, Alessandro, Vermeulen, Louis, Zlobec, Inti
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251036/ https://www.ncbi.nlm.nih.gov/pubmed/30385823 http://dx.doi.org/10.1038/s41416-018-0230-7

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