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The Role of IRE1 Signaling in the Central Nervous System Diseases

The accumulation of misfolded or unfolded proteins in endoplasmic reticulum (ER) lumen results in the activation of an adaptive stress process called the unfolded protein response (UPR). As the most conserved signaling branch of the UPR, Inositol-requiring enzyme 1 (IRE1) possesses both Ser/Thr kina...

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Detalles Bibliográficos
Autores principales: Ni, Haibo, Rui, Qin, Li, Di, Gao, Rong, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251047/
https://www.ncbi.nlm.nih.gov/pubmed/29663887
http://dx.doi.org/10.2174/1570159X16666180416094646