Propofol inhibited autophagy through Ca(2+)/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury

BACKGROUND: The neuroprotective role of propofol (PPF) in cerebral ischemia-reperfusion (I/R) has recently been highlighted. This study aimed to explore whether the neuroprotective mechanisms of PPF were linked to its regulation of Ca(2+)/CaMKKβ (calmodulin-dependent protein kinase kinase β)/AMPK (A...

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Detalles Bibliográficos
Autores principales: Sun, Bei, Ou, Hao, Ren, Fei, Huan, Ye, Zhong, Tao, Gao, Min, Cai, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251140/
https://www.ncbi.nlm.nih.gov/pubmed/30470173
http://dx.doi.org/10.1186/s10020-018-0054-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251140/
https://www.ncbi.nlm.nih.gov/pubmed/30470173
http://dx.doi.org/10.1186/s10020-018-0054-1

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