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Propofol inhibited autophagy through Ca(2+)/CaMKKβ/AMPK/mTOR pathway in OGD/R-induced neuron injury

BACKGROUND: The neuroprotective role of propofol (PPF) in cerebral ischemia-reperfusion (I/R) has recently been highlighted. This study aimed to explore whether the neuroprotective mechanisms of PPF were linked to its regulation of Ca(2+)/CaMKKβ (calmodulin-dependent protein kinase kinase β)/AMPK (A...

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Detalles Bibliográficos
Autores principales:	Sun, Bei, Ou, Hao, Ren, Fei, Huan, Ye, Zhong, Tao, Gao, Min, Cai, Hongwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251140/ https://www.ncbi.nlm.nih.gov/pubmed/30470173 http://dx.doi.org/10.1186/s10020-018-0054-1

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