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MicroRNA-133b/EGFR axis regulates esophageal squamous cell carcinoma metastases by suppressing anoikis resistance and anchorage-independent growth

BACKGROUND: Anoikis resistance has been demonstrated to facilitate distant metastases of cancers. MicroRNA-133b (miR-133b) is found to be down-regulated in various tumors, including esophageal squamous cell carcinoma (ESCC), and closely correlates with the malignant phenotype of ESCC. This study aim...

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Detalles Bibliográficos
Autores principales: Zhu, Jin-Feng, Liu, Yi, Huang, He, Shan, Li, Han, Zhi-Gang, Liu, Jun-Yuan, Li, Ying-Long, Dong, Xiang, Zeng, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251163/
https://www.ncbi.nlm.nih.gov/pubmed/30479571
http://dx.doi.org/10.1186/s12935-018-0684-y