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Cytotoxic and inflammatory potential of a phospholipase A(2) from Bothrops jararaca snake venom

BACKGROUND: Snake venom phospholipases A(2) (PLA(2)s) have been reported to induce myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This work aimed at the isolation and functional characterization of a PLA(2) isolated from Bothrops jararaca venom, named BJ-PLA(2)...

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Detalles Bibliográficos
Autores principales: Cedro, Rafhaella C. A., Menaldo, Danilo L., Costa, Tássia R., Zoccal, Karina F., Sartim, Marco A., Santos-Filho, Norival A., Faccioli, Lúcia H., Sampaio, Suely V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251196/
https://www.ncbi.nlm.nih.gov/pubmed/30498509
http://dx.doi.org/10.1186/s40409-018-0170-y