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Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

BACKGROUND: Glycosylation plays a critical role in the aggressiveness of pancreatic cancer (PC). Emerging evidences indicate significant involvement of cancer stem cells (CSCs) in PC aggressiveness. However, the importance of glycosylation in pancreatic cancer stem cells (PCSCs) is yet to be address...

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Detalles Bibliográficos
Autores principales: Barkeer, Srikanth, Chugh, Seema, Karmakar, Saswati, Kaushik, Garima, Rauth, Sanchita, Rachagani, Satyanarayana, Batra, Surinder K., Ponnusamy, Moorthy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251200/
https://www.ncbi.nlm.nih.gov/pubmed/30466404
http://dx.doi.org/10.1186/s12885-018-5074-2