Biological indicators of chemoresistance: an ex vivo analysis of γH2AX and p53 expression in feline injection-site sarcomas

BACKGROUND: The response of soft tissue sarcomas to cytotoxic chemotherapy is inconsistent. Biomarkers of chemoresistance or chemosensitivity are needed in order to identify appropriate patients for treatment. Given that many chemotherapeutics kill cells through direct DNA interactions, we hypothesi...

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Detalles Bibliográficos
Autores principales: Bing, Yike, Wund, Zacharie, Abratte, Tina, Borlle, Lucia, Kang, Susie, Southard, Teresa, Hume, Kelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251226/
https://www.ncbi.nlm.nih.gov/pubmed/30498397
http://dx.doi.org/10.1186/s12935-018-0690-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251226/
https://www.ncbi.nlm.nih.gov/pubmed/30498397
http://dx.doi.org/10.1186/s12935-018-0690-0

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