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Immunization of Experimental Dogs With Salivary Proteins From Lutzomyia longipalpis, Using DNA and Recombinant Canarypox Virus Induces Immune Responses Consistent With Protection Against Leishmania infantum

Metacyclic Leishmania promastigotes are transmitted by sand flies that inject parasites and saliva into the host's skin. Previous studies have demonstrated that DNA plasmids encoding Lutzomyia longipalpis salivary proteins LJM17 and LJL143, when used to immunize dogs, resulted in a systemic and...

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Detalles Bibliográficos
Autores principales: Abbehusen, Melissa Moura Costa, Cunha, Jurema, Suarez, Martha Sena, Teixeira, Clarissa, Almeida, Valter dos Anjos, Pereira, Laís da Silva, Bordoni, Marcelo, Gil-Santana, Leonardo, Solcà, Manuela da Silva, Fraga, Deborah Bittencourt Moté, Fischer, Laurent, Bozza, Patricia Torres, Veras, Patricia Sampaio Tavares, Valenzuela, Jesus G., Kamhawi, Shaden, Andrade, Bruno B., Brodskyn, Claudia I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251279/
https://www.ncbi.nlm.nih.gov/pubmed/30519235
http://dx.doi.org/10.3389/fimmu.2018.02558