Systematically investigating the key features of the DNase deactivated Cpf1 for tunable transcription regulation in prokaryotic cells

With a unique crRNA processing capability, the CRISPR associated Cpf1 protein holds great potential for multiplex gene regulation. Unlike the well-studied Cas9 protein, however, conversion of Cpf1 to a transcription regulator and its related properties have not been systematically explored yet. In t...

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Detalles Bibliográficos
Autores principales: Miao, Chensi, Zhao, Huiwei, Qian, Long, Lou, Chunbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251280/
https://www.ncbi.nlm.nih.gov/pubmed/30505961
http://dx.doi.org/10.1016/j.synbio.2018.11.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251280/
https://www.ncbi.nlm.nih.gov/pubmed/30505961
http://dx.doi.org/10.1016/j.synbio.2018.11.002

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