Ly9 (CD229) Antibody Targeting Depletes Marginal Zone and Germinal Center B Cells in Lymphoid Tissues and Reduces Salivary Gland Inflammation in a Mouse Model of Sjögren's Syndrome

Sjögren's Syndrome (SjS) is a common chronic autoimmune disease characterized by the B cell hyperactivation, lymphocyte infiltration, and tissue damage of exocrine glands. It can also present life-threatening extraglandular manifestations, such as pulmonary and hepatic involvement, renal inflam...

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Detalles Bibliográficos
Autores principales: Puñet-Ortiz, Joan, Sáez Moya, Manuel, Cuenca, Marta, Caleiras, Eduardo, Lazaro, Adriana, Engel, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251324/
https://www.ncbi.nlm.nih.gov/pubmed/30519241
http://dx.doi.org/10.3389/fimmu.2018.02661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251324/
https://www.ncbi.nlm.nih.gov/pubmed/30519241
http://dx.doi.org/10.3389/fimmu.2018.02661

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