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High Mortality in HIV-Associated Cryptococcal Meningitis Patients Treated With Amphotericin B–Based Therapy Under Routine Care Conditions in Africa

BACKGROUND: Cryptococcal meningitis (CM) causes 10%–20% of HIV-related deaths in Africa. Due to limited access to liposomal amphotericin and flucytosine, most African treatment guidelines recommend amphotericin B deoxycholate (AmB-d) plus high-dose fluconazole; outcomes with this treatment regimen i...

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Detalles Bibliográficos
Autores principales: Patel, Raju K K, Leeme, Tshepo, Azzo, Caitlin, Tlhako, Nametso, Tsholo, Katlego, Tawanana, Ephraim O, Molefi, Mooketsi, Mosepele, Mosepele, Lawrence, David S, Mokomane, Margaret, Tenforde, Mark W, Jarvis, Joseph N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251350/
https://www.ncbi.nlm.nih.gov/pubmed/30488038
http://dx.doi.org/10.1093/ofid/ofy267