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High Mortality in HIV-Associated Cryptococcal Meningitis Patients Treated With Amphotericin B–Based Therapy Under Routine Care Conditions in Africa
BACKGROUND: Cryptococcal meningitis (CM) causes 10%–20% of HIV-related deaths in Africa. Due to limited access to liposomal amphotericin and flucytosine, most African treatment guidelines recommend amphotericin B deoxycholate (AmB-d) plus high-dose fluconazole; outcomes with this treatment regimen i...
Autores principales: | Patel, Raju K K, Leeme, Tshepo, Azzo, Caitlin, Tlhako, Nametso, Tsholo, Katlego, Tawanana, Ephraim O, Molefi, Mooketsi, Mosepele, Mosepele, Lawrence, David S, Mokomane, Margaret, Tenforde, Mark W, Jarvis, Joseph N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251350/ https://www.ncbi.nlm.nih.gov/pubmed/30488038 http://dx.doi.org/10.1093/ofid/ofy267 |
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