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miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension

PURPOSE: miR-190a-5p expression alters dynamically in response to hypoxia. However, the role of miR-190a-5p expression in hypoxia-induced pulmonary hypertension (PH) remains unclear. We sought to correlate the miR-190a-5p expression levels with the severity, diagnosis, and prognosis of PH in relatio...

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Detalles Bibliográficos
Autores principales: Jiang, Jing, Xia, Yimeng, Liang, Yi, Yang, Meiling, Zeng, Wen, Zeng, Xiaocong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251363/
https://www.ncbi.nlm.nih.gov/pubmed/30538440
http://dx.doi.org/10.2147/COPD.S182504