The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

BACKGROUND & AIMS: The tumor-suppressor sterile α motif– and Src-homology 3–domain containing 1 (SASH1) has clinical relevance in colorectal carcinoma and is associated specifically with metachronous metastasis. We sought to identify the molecular mechanisms linking decreased SASH1 expression wi...

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Detalles Bibliográficos
Autores principales: Franke, Fabian Christoph, Müller, Johannes, Abal, Miguel, Medina, Eduardo Domínguez, Nitsche, Ulrich, Weidmann, Henri, Chardonnet, Solenne, Ninio, Ewa, Janssen, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251370/
https://www.ncbi.nlm.nih.gov/pubmed/30480076
http://dx.doi.org/10.1016/j.jcmgh.2018.08.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251370/
https://www.ncbi.nlm.nih.gov/pubmed/30480076
http://dx.doi.org/10.1016/j.jcmgh.2018.08.007

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