The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial–Mesenchymal Transition and Metastasis in Colorectal Cancer

BACKGROUND & AIMS: The tumor-suppressor sterile α motif– and Src-homology 3–domain containing 1 (SASH1) has clinical relevance in colorectal carcinoma and is associated specifically with metachronous metastasis. We sought to identify the molecular mechanisms linking decreased SASH1 expression wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Franke, Fabian Christoph, Müller, Johannes, Abal, Miguel, Medina, Eduardo Domínguez, Nitsche, Ulrich, Weidmann, Henri, Chardonnet, Solenne, Ninio, Ewa, Janssen, Klaus-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251370/
https://www.ncbi.nlm.nih.gov/pubmed/30480076
http://dx.doi.org/10.1016/j.jcmgh.2018.08.007

Ejemplares similares

Ejemplares similares