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Nitric oxide-releasing nanoparticles improve doxorubicin anticancer activity

PURPOSE: Anticancer drug delivery systems are often limited by hurdles, such as off-target distribution, slow cellular internalization, limited lysosomal escape, and drug resistance. To overcome these limitations, we have developed a stable nitric oxide (NO)-releasing nanoparticle (polystyrene-malei...

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Detalles Bibliográficos
Autores principales: Alimoradi, Houman, Greish, Khaled, Barzegar-Fallah, Anita, Alshaibani, Lama, Pittalà, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251458/
https://www.ncbi.nlm.nih.gov/pubmed/30538458
http://dx.doi.org/10.2147/IJN.S187089