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TPH-2 Gene Polymorphism in Major Depressive Disorder Patients With Early-Wakening Symptom
Background: Sleep disturbances, such as early wakening, are frequently observed in patients with major depressive disorder (MDD). The suprachiasmatic nuclei (SCN), which controls circadian rhythm, is innervated by the raphe nucleus, a region where Tryptophan hydroxylase-2 (TPH-2) gene is primarily e...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251472/ https://www.ncbi.nlm.nih.gov/pubmed/30519155 http://dx.doi.org/10.3389/fnins.2018.00827 |