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TPH-2 Gene Polymorphism in Major Depressive Disorder Patients With Early-Wakening Symptom

Background: Sleep disturbances, such as early wakening, are frequently observed in patients with major depressive disorder (MDD). The suprachiasmatic nuclei (SCN), which controls circadian rhythm, is innervated by the raphe nucleus, a region where Tryptophan hydroxylase-2 (TPH-2) gene is primarily e...

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Detalles Bibliográficos
Autores principales:	Tao, Shiwan, Chattun, Mohammad Ridwan, Yan, Rui, Geng, Jiting, Zhu, Rongxin, Shao, Junneng, Lu, Qing, Yao, Zhijian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251472/ https://www.ncbi.nlm.nih.gov/pubmed/30519155 http://dx.doi.org/10.3389/fnins.2018.00827

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