Cargando…

NAADP-dependent Ca(2+) signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

Middle East Respiratory Syndrome coronavirus (MERS-CoV) infections are associated with a significant mortality rate, and existing drugs show poor efficacy. Identifying novel targets/pathways required for MERS infectivity is therefore important for developing novel therapeutics. As an enveloped virus...

Descripción completa

Detalles Bibliográficos
Autores principales: Gunaratne, Gihan S., Yang, Yang, Li, Fang, Walseth, Timothy F., Marchant, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251489/
https://www.ncbi.nlm.nih.gov/pubmed/30121440
http://dx.doi.org/10.1016/j.ceca.2018.08.003